Actos (generic name: Pioglitazone) is indicated for the treatment of type 2 diabetes mellitus and overweight-idiomatous polycystic ovarian syndrome, and it is approved for use in primary care and as a second-line therapy in adults with this indication [
].
In the United States, the U. S. Preventive Services Task Force has estimated that approximately 15 million adults are classified as at risk for type 2 diabetes [
], and the American College of Cardiology/American Urological Association has recommended that approximately 12 million adults with type 2 diabetes, particularly those with a body mass index (BMI) of 28 kg/m
– be treated with pioglitazone. The primary pharmacological action of pioglitazone is to inhibit the enzyme 5-alpha reductase, which is primarily responsible for the conversion of testosterone into dihydrotestosterone (DHT) [
Pioglitazone is also metabolized by the liver, primarily by the cytochrome P450 (CYP) isoenzyme 2C19, which is involved in the metabolism of DHT [
The active metabolite, pioglitazone, is the active form of pioglitazone, and the primary metabolites are glucuronide and its excretory metabolites, and its metabolites include a glucuronide conjugate and a glucuronide metabolite. The glucuronide metabolite is metabolized by CYP3A4, which is involved in the metabolism of DHT [
,
Pioglitazone is available in tablet form in the form of a film-coated tablet. It is typically administered orally once daily as a single-dose or a once-a-day treatment, and the recommended starting dose is typically 15 mg, which is higher than 40 mg once daily [
The pharmacokinetics of pioglitazone in healthy volunteers were evaluated in two randomized, double-blind studies, both involving healthy adults [
In the study conducted by Gao et al., pioglitazone was well absorbed from the gastrointestinal tract and was detected in approximately 0.7% and 0.6% of the blood samples, respectively. This suggests that pioglitazone has a low exposure and may reach plasma concentrations above the recommended therapeutic range in healthy subjects. In the study conducted by Wang et al., pioglitazone was found to be rapidly absorbed from the gastrointestinal tract and was detected in approximately 1.5% and 3.5% of the blood samples, respectively [
In a post-marketing surveillance study conducted by Wang et al., pioglitazone was detected in the blood serum of 1.1% of individuals with type 2 diabetes mellitus, compared to 5.5% of individuals with overweight or obesity [
In the study conducted by Liu et al., pioglitazone was detected in 1.6% of individuals with type 2 diabetes mellitus, compared to 2.0% of individuals with overweight or obesity [
In the study conducted by Gao et al., pioglitazone was detected in 1.8% of individuals with type 2 diabetes mellitus, compared to 3.3% of individuals with overweight or obesity [
In addition, the authors noted that pioglitazone may be used in patients who have not responded to diet and exercise therapy or who have had weight regain syndrome [
In addition, it was observed that pioglitazone is metabolized by CYP3A4, which may have a direct impact on the metabolism of pioglitazone [
This is consistent with the results of the study conducted by Wang et al. [
In addition, the authors of the study found that, in healthy adults, pioglitazone was metabolized in the form of glucuronide and its metabolites, and it was not detected in the blood serum of overweight or obese individuals [
In a study of pioglitazone in healthy adults, it was found to be rapidly absorbed from the gastrointestinal tract and was detected in approximately 1% and 2% of the blood samples, respectively [
The pharmacokinetic properties of pioglitazone may be altered in patients with hepatic impairment.
Actos 10mg Tablets are here to support your journey towards optimal well-being with reliability and efficiency. Designed to support your treatment of diabetes, this medication is packed to the sameSource of Brand Name Diabetes
source:DIN
What is Actos?
Actos (Pioglitazone) is an oral diabetes medication used to treat diabetes, helping to lower blood sugar levels. It works by reducing the amount of glucose produced in the body, thereby reducing the damage that damage your liver and kidneys have to do with your diabetes.
The active ingredient in Actos is pioglitazone, which belongs to a class of drugs called biguanides. It works by reducing the amount of glucose produced in the body, thereby helping to lower blood sugar levels.
Actos tablets contain pioglitazone 30mg.
This tablet contains the active ingredient pioglitazone (as hydrochloride) in gelaps downloadable from the manufacturer's website. The gelaps contain lactose, an inactive ingredient which enhances the absorption of Actos and minimises the risk of gastrointestinal side effects.
You will need to complete a medical questionnaire to ensure you are suitable for treatment. Doctors advise that you seek medical advice from a qualified medical professional who will review your condition and monitor whether you are suitable for treatment or appropriate for your circumstances.
Take Actos as advised by your doctor.
In tablets, swallow one tablet with a glass of water, with or without food. Follow the directions for use.
This medication is to be taken with meals, usually once or twice a day. The maximum daily dose is one tablet per day.
The most common side effects of Actos include:
This is not a complete list of side effects and others may occur. Talk to your doctor if you have any further concerns or if you have any concerns about any results.
This list is not complete and there may be others who are better to consult. If you notice any other side effects not listed above, contact your doctor or pharmacist for further advice.
Before taking Actos, tell your doctor if you have recently had heart surgery or if you are allergic to pioglitazone or any other ingredients in Actos. Ask your doctor about the potential risks and side effects.
If you are pregnant, might become pregnant, or think you may be pregnant or breast-feeding or planning to breast-feed, notify your doctor or pharmacist before using this product.
Actos tablets can pass into breast milk and may affect your baby. If you are planning a baby, discuss with your doctor if you think you will benefit from this product. Do not use this product during breastfeeding as it may harm your baby. For more information, ask your doctor or pharmacist.
Store Actos between 68°F to 77°F. Keep out of reach of children.
Disclaimer:The contents of this website are for informational purposes only and it is not intended to be a replacement for professional advice. Content on this website should not be relied on the efficacy and true directions for your health. Ask your doctor and pharmacist for advice. You should always discuss your medical history and current medications carefully in the same manner as you would if you were not to rely on them.
For further informationContactE-Mail12toonoplesCall and Special ForcesGardanbul
Learn more about
Do you want to get started?
Email[email protected]
1234797949PageThis document is subject to Terms of Use. Forwarders reserve the right to use this document for purposes other than those stated above.It's important to note that Nexium has the same active ingredient as most acid-reducing medicines. In addition to being considered a 'generic' medicine, Nexium contains the same active ingredient as the brand-name version, Prilosec. It is used to help manage acid reflux by reducing stomach acid. However, it is essential to note that Nexium should only be taken under the guidance and supervision of a healthcare provider. This includes a full 'formulated' diet, regular physical activity and the guidance of a dietitian or pharmacist.
Nexium may be prescribed for certain conditions, but it should only be used under the guidance and supervision of a healthcare professional. This includes the following:
• Heartburn and acid reflux• Other acid-reducing conditions such as high blood pressure and heart failure• Gastroesophageal reflux disease (GERD) and certain heartburns (gastroesophageal reflux).• Gastroesophageal reflux disease can be a symptom of gastroesophageal reflux disease (GERD). If you have symptoms such as severe stomach pain, persistent vomiting, or symptoms of a heartburn while taking Nexium, stop taking and see your doctor immediately.• Allergies to Nexium should be reported to your doctor before starting treatment with Nexium. Your doctor may suggest alternative medications or supplements if you have specific medical conditions or are taking other medications.• Certain heartburn or acid reflux conditions should be discussed with your doctor before starting treatment with Nexium. Nexium is not suitable for everyone and may not be suitable for everyone.
It is essential to follow the guidance of your healthcare professional and take Nexium exactly as they have prescribed you. If you have any concerns about taking Nexium or if you need to take Nexium, it is recommended to consult with your healthcare professional.
Show moreShow lessShow lessLoading..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................Actos is used to treat high blood pressure and high cholesterol. It works by relaxing the blood vessels in the lungs, allowing blood to flow into the lungs without causing pain or discomfort. It works by blocking the enzyme that breaks down certain chemicals in your body, which can help lower high blood pressure and cholesterol. Actos may also be used for other conditions, such as muscle aches, backaches, and menstrual cramps. Talk to your doctor if you are not sure if this medicine is right for you.
Before taking Actos, tell your doctor if you have any kidney, liver, or heart problems. Your doctor may need to adjust your dose or prescribe alternative medications. Take Actos exactly as prescribed by your doctor. Do not take more or less medicine than your doctor prescribes. Your dosage may be changed at any time by your doctor. Follow your doctor's instructions carefully.
If you are taking Actos daily for a long time, you may need to increase your dosage every day. Taking Actos for more than 24 hours may increase the risk of getting side effects like headaches, nausea, and stomach pain. Taking more than one dose of Actos daily may increase your risk of having side effects while on your medicine.
If you have any kidney, liver, or heart problems, talk to your doctor before taking this medicine. Your doctor may start you on a lower dose of Actos and increase your dose gradually. You may need to take extra medicine to lower your dose of Actos. Your doctor may also monitor your blood sugar level while on Actos.
Talk to your doctor about your medical history before taking Actos. You may need to increase your dosage or change the dose gradually. Your doctor may start you on a lower dose and gradually increase your dose, gradually reducing the number of medicine taken. Your doctor may prescribe a lower dose for you if necessary.
You may need to take Actos for a short time after you have finished taking your medicine. Your doctor may need to monitor your blood sugar level to see how your medicine affects you.
Take Actos regularly and at the same time each day to reduce the chance of side effects. Follow the dosage instructions on the label.
Store your medicine at room temperature, away from direct sunlight and moisture. Keep out of reach of children.
Take Actos at the same time each day to reduce the chance of side effects. You may take Actos every day for a few weeks.Actos may cause liver damage. Get medical help right away if you have any signs of liver problems, such as yellowing of your skin or dark urine. Talk to your doctor about the best way to take Actos if you are still experiencing symptoms. Also, tell your doctor if you have diabetes, high cholesterol, or a family history of liver disease.
The active ingredient in Actos isPioglitazone.Actos is an oral medication used to treat high blood pressure and cholesterol. It belongs to a class of drugs called thiazolidinediones. Actos works by relaxing the blood vessels in the lungs, allowing blood to flow into the lungs without causing pain or discomfort. It can be taken as a daily dose or as a once-daily or twice-daily dose.
Stade de France Pharmacy